Research Articles
The Cellular Betrayal: How a Rogue Protein Fuels Cancer's Spread
Discover how the MSK1 protein stabilizes Snail through USP5-mediated deubiquitination, driving colorectal cancer metastasis.
MDM2: The P53-Independent Driver of Breast Cancer's Deadly Spread
Groundbreaking research reveals MDM2's independent role in driving breast cancer metastasis through pathways separate from p53, opening new treatment possibilities.
The Double Agent: How a Classic Tumor Suppressor Reveals a New Face in Cancer Spread
Discover how DLC1, a classic tumor suppressor, reveals surprising RhoGAP-independent functions in cancer invasion and metastasis.
The Cellular Saboteur: How Rogue Proteins Help Liver Cancer Spread
Discover how USP1 protein deactivates cellular self-destruct signals in liver cancer cells, enabling metastasis and offering new therapeutic targets.
Cracking Cancer's Invasion Code: How a Cellular Switch Drives Colorectal Cancer Spread
Discover how the MEK/ERK-ZEB1-USP10 pathway controls colorectal cancer metastasis and the therapeutic implications of this molecular switch.
Acetyl Code Unlocked: How a Molecular Switch Turns ZEB1 Into a Cancer Metastasis Machine
Breakthrough research reveals how K811 acetylation transforms ZEB1 into a lethal driver of lung cancer metastasis through protein stabilization and NuRD complex recruitment.
Silencing the Storm: How a Bone Drug Halts Prostate Cancer's Stealth Spread
New research reveals how Zoledronic acid dismantles EMT's machinery by targeting NEDD9, silencing prostate cancer's invasive voice.
The Betrayal Within: How Activin Hijacks Cellular Defenses to Fuel Colon Cancer's Spread
Discover how colon cancer cells manipulate the p21 pathway through Activin, PI3K, NF-κB and MDM2 to promote metastasis.